Table 2.

Quantification of ultrastructural variables of hippocampal MFT in control, restraint-stressed, diabetic-stressed, and Cort-treated rats

Morphological parameter	Control	Control + R	STZ	STZ + R	Cort, 400 μg/ml
Total MFT profile area, μm2	5.12  ± 0.24	5.40  ± 0.30	5.76  ± 0.34	5.64  ± 0.41	7.24  ± 0.23*
Mit profile area/MFT profile, μm2	0.28  ± 0.01	0.26  ± 0.04	0.40  ± 0.04*†	0.28  ± 0.03	0.28  ± 0.04
% decrease synaptic vesicle	—	2.64  ± 0.18	21.05  ± 1.80‡	42.99  ± 2.99§	39.20  ± 0.31§  (85% of MFT)
density					2.80  ± 0.20  (15% of MFT)

* and  

^†, P < 0.05 compared with control, control + restraint groups, and STZ + restraint group;  

^‡ and  

^§, P < 0.05 and 0.01, compared with control and control + restraint groups. One-way ANOVA, Tukey post hoc test. No significant differences between controls and controls receiving 2.4% ethanol (see Materials and Methods) were detected. No significant differences on number or area of spine profiles or number of mitochondria/MFT profile were detected among experimental treatment groups (data not shown). R, restraint stress.