Figure 3.

Cardiac-specific ΔH2-R19 mini-dystrophin expression eliminates fibrosis in the heart but not in the diaphragm. (a) Representative Masson trichrome staining photomicrographs from the heart (top row) and the diaphragm (bottom row) in 22-month-old BL10, mdx, and transgenic line 951 mice. Connective tissue is in blue color. (b) Heart hydroxyproline content normalized by dry tissue weight. N, sample size. Asterisk, result from mdx mice was significantly different from both BL10 and transgenic mice. There was no statistical difference between BL10 and transgenic mice.