Figure 6.

Cardiac-specific ΔH2-R19 mini-dystrophin expression improves uphill running performance without enhancing limb muscle strength. (a) Running distance and body weight in 8-month-old male mice. (b) Running distance in 18-month-old male mice (note, different treadmill protocols were used for 8- and 18-month-old mice). (c) Body weight normalized forelimb grip-strength in 18-month-old mice. N, sample size; Tg, transgenic mice; asterisk, significantly higher than all other groups; hash, significantly higher than that of mdx mice but lower than that of BL10 mice.