Table 2.
Summary of maximal local and systemic reactogenicity.
| Symptom, intensity | All vaccines (n = 15) |
|---|---|
| Local reactogenicity | |
| Pain/tenderness | |
| None | 2 (13.3) |
| Mild | 11 (73.3) |
| Moderate | 2 (13.3) |
| Swelling | |
| None | 6 (40.0) |
| Mild | 9 (60.0) |
| Moderate | 0 |
| Redness | |
| None | 5 (33.3) |
| Mild | 10 (66.7) |
| Moderate | 0 |
| Any local symptom | |
| None | 1 (6.7) |
| Mild | 12 (80.0) |
| Moderate | 2 (13.3) |
| Systemic reactogenicity | |
| Malaise | |
| None | 11 (73.3) |
| Mild | 3 (20.0) |
| Moderate | 1 (6.7) |
| Myalgia | |
| None | 13 (86.7) |
| Mild | 0 |
| Moderate | 2 (13.3) |
| Headache | |
| None | 11 (73.3) |
| Mild | 3 (20.0) |
| Moderate | 1 (6.7) |
| Chills | |
| None | 14 (93.3) |
| Mild | 0 |
| Moderate | 1 (6.7) |
| Nausea | |
| None | 14 (93.3) |
| Mild | 0 |
| Moderate | 1 (6.7) |
| Temperature | |
| None | 15 (100) |
| Mild | 0 |
| Moderate | 0 |
| Any systemic symptom | |
| None | 9 (60.0) |
| Mild | 4 (26.7) |
| Moderate | 2 (13.3) |
NOTE. Data are no. (%) of subjects, unless otherwise indicated. Local injection site reactions were recorded by clinicians 30−45 min after an injection and were then recorded as self-assessments at home by subjects on a 5-day diary card. Systemic reactions were recorded as self-assessments at home by subjects on a 5-day diary card after each injection. There were no reports of severe local or systemic symptoms after vaccination.