Table 2.
Methamphetamine and amphetamine mass per sweat patch worn for 15 h at the end of each day after administration of 4 daily low (10 mg) or high (20 mg) MAMP doses.
| MAMP | AMP | MAMP | AMP | MAMP | AMP | MAMP | AMP | |
|---|---|---|---|---|---|---|---|---|
| Low dose | ||||||||
| n | 8 | 8 | 7 | 7 | 8 | 8 | 8 | 8 |
| ≥LOQ, na | 5 | 0 | 5 | 3 | 5 | 2 | 6 | 3 |
| Median ng/patch (range) |
11.2 (5.3–42.3) |
ND | 32.5 (5.0–82.1) |
9.5 (2.9–9.8) |
5.9 (2.8–72.4) |
10.2 (8.0–12.4) |
23.7 (16.8–104) |
4.8 (2.8–20.1) |
| ≥25 ng/patch, n | 1 | 0 | 3 | 0 | 1 | 0 | 3 | 0 |
| ≥SAMHSA, nb | 0 | 0 | 2 | 0 | 1 | 0 | 2 | 0 |
| High dose | ||||||||
| n | 4 | 4 | 4 | 4 | 3 | 3 | 3 | 3 |
| ≥LOQ, na | 4 | 3 | 3 | 3 | 3 | 3 | 3 | 2 |
| Median ng/patch (range) |
28.3 (18.9–103) |
5 (3.3–8.4) |
70.6 (22.7–215) |
15.8 (5.1–21.5) |
68.5 (15.8–148) |
8.5 (3.9–19.4) |
17.1 (11.5–74.8) |
8.1 (5.2–11.0) |
| ≥25 ng/patch, n | 2 | 0 | 2 | 0 | 2 | 0 | 1 | 0 |
| ≥SAMHSA, nb | 2 | 0 | 2 | 0 | 2 | 0 | 1 | 0 |
a
LOQ 2.5 ng/patch.
b
Criteria for MAMP positive result: MAMP ≥25 ng/patch, AMP ≥ limit of detection.