Table 2. Gene Ontogeny (GO) Analysis.
Category | GO term | #Of Genes (%) | p-value | Benjamini-Hochberg |
Molecular Function | Actin binding | 25 (45.5) | 4.7×10−31 | 1.3×10−27 |
Cytoskeletal protein binding | 27 (49.1) | 1.4×10−30 | 1.8×10−27 | |
Calmodulin binding | 10 (18.2) | 2.3×10−11 | 2.1×10−8 | |
Motor Activity | 10 (18.2) | 3.9×10−10 | 2.7×10−7 | |
Cellular Component | Cytoskeleton | 33 (60.0) | 2.0×10−29 | 1.6 ×10−26 |
Actin cytoskeleton | 21 (38.2) | 6.8×10−26 | 2.7×10−23 | |
Non-membrane bound organelle | 35 (63.6) | 4.4×10−25 | 1.1×10−22 | |
Cytoskeletal part | 20 (36.4) | 4.8×10−16 | 7.0×10−14 | |
Myosin complex | 10 (18.2) | 1.1×10−13 | 1.4×10−11 | |
Biological Processes | Cytoskeletal organization | 19 (34.5) | 2.2×10−16 | 1.2×10−12 |
Actin filament-based process | 14 (25.5) | 2.8×10−15 | 7.2×10−12 | |
Actin cytoskeleton organization | 12 (21.8) | 1.8×10−12 | 3.1×10−9 |
List of the most statistically significant GO terms resulting from analysis between enriched genes and the entire mouse genome background set. The number and percentage of genes in each category are provided. The p-value (EASE score) indicates the probability that these genes are enriched in these categories due to random chance. The Benjamini-Hochberg score globally corrects enrichment p-values to account for multiple testing.