Skip to main content
. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Immunol. 2009 May 1;182(9):5446–5452. doi: 10.4049/jimmunol.0804052

Figure 1.

Figure 1

LAIR-1 Arg 65 is a critical residue for collagen recognition leading to signal transmission. A) Relative levels of β-galactosidase activity generated by culture of BWZ.36 or BWZ.36 LAIR-1/CD3ζ cells (upper panel); or BWZ.36 KIR2DL2/CD3ζ cells (lower panel) on uncoated plates or coated with collagen type I, -type IV, anti-LAIR-1 mAb, anti-KIR2DL2 mAb or isotype control Ig. B) BWZ.36 or BWZ.36 LAIR-1/CD3ζ cells on uncoated plates or coated with matrigel or laminin. C) BWZ.36 LAIR-1/CD3ζ wt or BWZ.36 LAIR-1/CD3ζ R65K cells on uncoated plates or coated with collagen type I, -type IV, anti-LAIR-1 mAb or isotype control Ig. Each experiment was performed 3−5 independent times.