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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Immunol. 2009 May 1;182(9):5446–5452. doi: 10.4049/jimmunol.0804052

Figure 5.

Figure 5

Recombinant LAIR-1/Fc R65K binds to transmembrane collagen XVII with lower avidity than recombinant LAIR-1/Fc wt. Upper panels show staining with anti-collagen XVII mAb of untransfected (upper left) and collagen XVII transfected (upper right) K562 cells. Filled histograms represent the binding of anti-collagen XVII mAb and empty histograms the binding of isotype control Ig. The lower panel shows binding of the LAIR-1/Fc wt, LAIR-1/Fc R65K and ICAM-1/Fc fusion proteins to untransfected (empty symbols) and collagen XVII transfected (filled symbols) K562 cells. Results are representative of two independent experiments.