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. 2009 Aug 3;4(8):e6483. doi: 10.1371/journal.pone.0006483

Table 1. Patient's characteristics.

Categorical data
Variables Development dataset 429 cases (%) Validation dataset 409 Cases (%)
Men 296 (68) 203 (49)
Women 133 (32) 206 (51)
PS = 0 141 (33) 57 (14)
PS = 1 138 (32) 129 (31)
PS = 2 108 (25) 103 (25)
PS = 3 35 (9) 93 (23)
PS = 4 4 (1) 26 (7)
Absence of co-morbidity or co- morbidity not requiring treatment 241 (56) 264 (66)
At least 1 co-morbidity requiring treatment 172 (44) 141 (34)
Number of met. site = 1 168 (39) 184 (45)
Number of met. site = 2 107 (25) 130 (31)
Number of met. site = 3 85 (20) 59 (14)
Number of met. site = 4 43 (10) 23 (7)
Number of met. site≥5 26 (6) 13 (3)
Adenocarcinoma 272 (63) 210 (51)
Undifferentiated carcinoma 58 (13) 138 (34)
Squamous cell carcinoma 77 (18) 24 (6)
Others 22 (6) 37 (9)
Lung met. 103 (24) 88 (21)
Liver met. 144 (33) 174 (42)
Bone met. 156 (36) 117 (28)
Brain met. 32 (8) 1 (0)
Continuous
Variables (units) Development dataset Median (range) Validation dataset Median (range)
Age (years) 59 (22–91) 65 (19–92)
LDH (IU/l) 660 (57–10,084) 428 (86–7,538)
Alkaline phosphatase (IU/l) 280 (31–7,423) Not done
Hemoglobin level (g/dl) 12.5 (6–17,3) 12.3 (6–18.2)
Platelets (U/mm3) 320,000 (7,000–830,000) 374,000 (10,000–736,000)
Lymphocytes (U/mm3) 1,300 (220–6,830) 1,250 (100–99,2000)
Variables Development dataset 429 cases (%) Validation dataset Cases (%)
Protein levels (g/l) 68 (49–92) 69 (42–87)
Albumin levels (g/l) 32 (14–51) 36 (19–49)

Abbreviations: PS = performance status, met. = metastasis, LDH = lactate dehydrogenase, ULN = upper limit of normal, IU: international unit, U:unit.