Table 2.
Baseline characteristics
| Characteristics | Caucasian | African-American | Hispanic | Total cohort |
|---|---|---|---|---|
| Sample size, n (%) | 705 (27.6) | 797 (31.2) | 1,054 (41.2) | 2,556 (100) |
| Mortality n (%) | ||||
| Deceased | 111 (15.7) | 168 (21.1) | 148 (14.0) | 427 (16.7) |
| Alive | 594 (84.3) | 629 (78.9) | 906 (86.0) | 2,129 (83.3) |
| Age at baseline, mean ± SD | 77.3 ± 6.9 | 77.2 ± 6.5 | 76.6 ± 6.4 | 77.0 ± 6.6 |
| Sex, n (%)* | ||||
| Male | 271 (38.4) | 250 (31.4) | 346 (32.8) | 867 (33.9) |
| Female | 434 (61.6) | 547 (68.6) | 708 (67.2) | 1,689 (66.1) |
| Education, mean ± SD* | 13.0 ± 3.5 | 10.9 ± 3.8 | 6.7 ± 4.3 | 9.7 ± 4.8 |
| Body mass index, mean ± SD | 26.5 ± 5.1 | 27.8 ± 6.3 | 27.7 ± 5.1 | 27.4 ± 5.5 |
| Cholesterol (mg/dl), mean ± SD | 202.3 ± 38.5 | 200.5 ± 38.0 | 198.4 ± 41.1 | 200.1 ± 39.6 |
| Non-HDL cholesterol (mg/dl), mean ± SD* | 154.6 ± 37.9 | 148.5 ± 36.6 | 154.0 ± 40.5 | 152.4 ± 38.5 |
| HDL (mg/dl), mean ± SD* | 47.8 ± 14.8 | 51.9 ± 16.0 | 44.5 ± 13.7 | 47.7 ± 15.1 |
| Triglycerides (mg/dl), mean ± SD* | 157.3 ± 84.5 | 129.4 ± 67.9 | 176.0 ± 94.7 | 156.3 ± 86.5 |
| LDL (mg/dl), mean ± SD | 123.1 ± 32.6 | 122.7 ± 34.2 | 118.7 ± 36.0 | 121.2 ± 34.6 |
| APOE ε4 allele, n (%)*a | ||||
| 2/4, 3/4, 4/4 | 153 (22.1) | 279 (35.3) | 262 (25.3) | 694 (27.6) |
| 2/2, 2/3, 3/3 | 538 (77.9) | 512 (64.7) | 775 (74.7) | 1,825 (72.4) |
| Heart disease, n (%)*a | ||||
| Yes | 211 (31.2) | 161 (21.0) | 220 (21.8) | 592 (24.2) |
| No heart disease | 465 (68.8) | 605 (79.0) | 788 (78.2) | 1,858 (75.8) |
| Hypertension, n (%)*a | ||||
| Yes | 354 (52.4) | 524 (68.5) | 717 (71.3) | 1,595 (65.2) |
| No hypertension | 321 (47.6) | 241 (31.5) | 289 (28.7) | 851 (34.8) |
| Diabetes, n (%)*a | ||||
| Yes | 80 (11.9) | 168 (21.9) | 260 (25.8) | 508 (20.7) |
| No diabetes | 595 (88.1) | 598 (78.1) | 748 (74.2) | 1,941 (79.3) |
| Stroke, n (%)a | ||||
| Yes | 60 (8.9) | 84 (11.0) | 121 (12.0) | 265 (10.8) |
| No stroke | 618 (91.1) | 682 (89.0) | 888 (88.0) | 2,188 (89.2) |
| Dementia status, n (%)* | ||||
| Incident | 28 (4.0) | 96 (12.1) | 177 (16.8) | 301 (11.8) |
| No | 677 (96.0) | 701 (87.9) | 877 (83.2) | 2,255 (88.2) |
| Smoking status, n (%)* | ||||
| Currently smoking | 59 (8.4) | 137 (17.2) | 84 (8.0) | 280 (10.9) |
| Not currently smoking | 646 (91.6) | 660 (82.8) | 970 (92.0) | 2,276 (89.1) |
*
P<0.05.
a
Numbers are less than 2,556 due to missing data.