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. 2008 Oct-Dec;1(1):25–32. doi: 10.4161/oxim.1.1.6856

Figure 2.

Figure 2

The NOS/NO signaling pathways that regulate AJ and TJ dynamics in the testes. This is a simplified schematic diagram summarizing recent studies regarding the role of the NOS/NO signaling pathway that regulates junction dynamics in the testis using the Adjudin model.42–44 AJ, adherens junction; ES, elongated spermatid; JAM, junctional adhesion molecule; MC, myoid cells; N, Sertoli cell nucleus; NO, nitric oxide; NOS, nitric oxide synthase; PKG, protein kinase G; PS, pachytene spermatocyte; RS, round spermatid; SC, Sertoli cell; sGC, soluble guanylyl cyclase; SPC, preleptotene/leptotene spermatocyte; SPG, spermatogonium; TJ, tight junction; ZO-1, zonula occludens-1.