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. 2009 May 25;37(13):4430–4440. doi: 10.1093/nar/gkp422

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© 2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Effect of an AP site on (A) the efficiency of excision of Tg. by Nth (1 pg to 1 ng) and (B) the dependence for formation of a DSB on the concentration of Nth determined following native PAGE. Effect of 8-oxoG on the efficiency of excision of Tg. by Nth (1 pg to 10 ng) (C) or Nei (0.05–1 U) (D). Effect of Tg on the efficiency of excision of 8-oxoG by Fpg (1 pg to 10 ng) (E). The fold inhibition was obtained from comparison with the control containing only Tg (A–D) or 8-oxoG (E). The error bars represent the standard deviation from three different experiments.