Fig. 5.
Decreased mitochondria in AMD retina. The number of mitochondria (M) is much lower in the inner segment of photoreceptors of the AMD eye (A) as compared with a normal age-control eye (B). Accumulation of lipofuscin is known to autofluoresce (in yellowish green color) in the RPE and drusen of the AMD eye (green: immunofluorescence staining with anti-human COV IV, a specific marker of mitochondria).