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CARΔD2 does not rescue infection of cells with adenoviruses with elongated fibers. CHO cells expressing CAR, CARΔD2, or CARD0 were infected with Ad-GL, Ad-IGL, or Ad-IIGL at a dose of 1,000 pt/cell. At 48 h, cells were analyzed for luciferase activity per milligram protein (n = 3, one representative experiment shown). Elongating the Ad fiber does not rescue infection via CARΔD2.
