TABLE 3.

PECAM IMMUNOREACTIVITY IN THE LUNGS OF TREATED AND CONTROL MICE

Groups	PECAM-Positive Tissue VD (%)
A. RA Experiment
Control	59.2 ± 0.0
RA	59.2 ± 0.2
SU1498	48.7 ± 0.2*
RA+SU1498	51.5 ± 0.7
B. EPO Experiment
Control	55.8 ± 1.5
EPO	56.1 ± 0.4
SU1498	43.3 ± 0.8*
EPO+SU1498	50.3 ± 0.1

Definition of abbreviations: EPO, eryhtropoietin; PECAM, platelet endothelial cell adhesion molecule; RA, retinoic acid; VD, volume density.

Morphometric analysis was performed to determine the VD of lung tissue immunoreactive for PECAM, a marker for endothelial cells. Values are expressed in the table as the mean ± SEM (n = 3–8).

^*P < 0.05 versus control, RA, or EPO.