TABLE 1.
Lung histologic scores
| Chimera | Time after Infection |
Inflammation PB, PV, A |
Necrosis B, V, A |
Predominant Inflammatory Cell Type |
Combined Injury Score (Necrosis + Inflammation) |
|---|---|---|---|---|---|
| M88→M88 | 4 h | 0.625 | 0 | Mononuclear | 0.625 |
| 24 h | 7.75 | 5.75 | PMN | 13.50 | |
| WT→M88 | 4 h | 0.5 | 0 | Mononuclear | 0.5 |
| 24 h | 4.125 | 0 | PMN | 4.125 | |
| WT→WT | 4 h | 3.5 | 0.25 | PMN | 3.75 |
| 24 h | 4.125 | 0.5 | PMN | 4.625 | |
| M88→WT | 4 h | 1.625 | 0 | PMN | 1.625 |
| 24 h | 2.375 | 0 | PMN | 2.375 |
Definition of abbreviations: A, alveolar; B, bronchiolar; PB, peribronchial; PV, perivascular; V, vascular.
n = 4 for each group at each time point, mean value shown.