Table 3.
PTPN11 rs2301756 genotype distribution according to H. pylori seropositivity and the grade of gastric atrophy.
| Genotype | H. pylori seronegative | H. pylori seropositive | ||||
|---|---|---|---|---|---|---|
| GA (-) | GA (+) | GA (++) | GA (-) | GA (+) | GA (++) | |
| G/G | 447 (68.3%) | 11 (64.7%) | 25 (89.3%) | 293 (68.4%) | 223 (68.2%) | 127 (75.6%) |
| G/A | 189 (28.9%) | 6 (35.3%) | 3 (10.7%) | 135 (28.9%) | 93 (28.4%) | 38 (22.6%) |
| A/A | 18 (2.8%) | 0 (0.0%) | 0 (0.0%) | 14 (2.7%) | 11 (3.4%) | 3 (1.8%) |
| Total | 654 (100%) | 17 (100%) | 28 (100%) | 442 (100%) | 327 (100%) | 168 (100%) |
GA(-), GA(+) and GA(++) indicate no atrophy, mild atrophy and severe atrophy, respectively.