Table 1.

Comparison of giant cell tumor and central giant cell granuloma

	Giant cell tumor	Central giant cell granuloma
Location	Sphenoid, temporal, ethmoid bones (endochondral ossification, not membranous in origin) Jaws in paget disease	Jaws, anterior mandible
Giant cells	Evenly distributed	Fewer, smaller giant cells, unevenly distributed
Stromal cells	Monocytes, osteoclasts No intercellular collagen	Fibroblasts producing collagen; Numerous capillaries
Osteoid	No	Yes