Table 1.
Cooperation of Sdc and Dlp in Slit signalling
| Driver | Mutant | Axon midline crossing, % segment/embryo |
|---|---|---|
| None | wt | 0 (n = 209) |
| None | sdc− | 19 (n = 198) |
| None | ttv− | 0 (n = 220) |
| None | dlp− | 0 (n = 220) |
| None | sdc−;ttv− | 39 (n = 198) |
| None | sdc−;dlp− | 50 (n = 176) |
| None | wt | 0 (n = 220) |
| None | sdc− | 19 (n = 176) |
| simG4:UAS-sdc | sdc− | 19 (n = 198) |
| repoG4:UAS-sdc | sdc− | 16 (n = 231) |
| elavG4:UAS-sdc | sdc− | 0 (n = 209) |
| simG4:UAS-dlp | sdc− | 11 (n = 231) |
| repoG4:UAS-dlp | sdc− | 5 (n = 220) |
| elavG4:UAS-dlp | sdc− | 9 (n = 198) |
The percentages of segments with ventral midline crossover of ipsilateral axon fascicles stained with anti-FASII antibody are listed. n, number of segments analyzed. Analyzed embryos were wt, sdc, ttv, dlp, sdc;ttv, and sdc;dlp homozygous mutants as well as sdc homozygous mutants rescued with UAS-sdc-PA or UAS-dlp expressed in Slit-secreting midline cells (simG4), intermediate glia tissue (repoG4), or axonal target tissue (elavG4).