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A simplified Maximum-Likelihood phylogeny of the mitochondrial clan. Vertebrate and arthropod steroidogenic enzymes are highlighted in blue and green, respectively, and the molecules they produce are indicated. These molecules are 20-OH Ecdysone for CYP314, Ecdysone for CYP315, 2deoxyecdysone for CYP302, pregnenolone for CYP11A, and cortisol for CYP11B. Colored residues in the chemical formulas are those that are modified by the catalytic reaction.
