Skip to main content
. 2009 May 18;53(8):3572–3575. doi: 10.1128/AAC.00176-09

TABLE 1.

QRDR genetic backgrounds and quinolone MICs

S. pneumoniae strain QRDR genetic backgrounda
MIC (μg/ml)
parC gyrA CIP LVX GAT MXF GAR
W001 wt wt 0.5 0.5 0.12 0.06 0.015
W002 wt wt 0.25 0.25 0.12 0.06 0.015
S001 Asp83Asn wt 2 1 0.25 0.12 0.03
S002 Ser79Phe wt 2 1 0.12 0.25 0.06
S003 wt Ser81Phe 0.5 0.5 0.12 0.06 0.06
S004 wt Gly85Asn 0.5 1 0.25 0.12 0.06
D001 Ser79Phe Gly85Lys 32 16 4 4 0.25
D002 Ser79Phe Ser81Phe 8 16 8 4 0.5
a

wt, wild type.