TABLE 1.
Susceptibilities of bacterial strains to MurF inhibitors DQ1 and DQ2
| Strain | MIC (μg/ml)
|
||||
|---|---|---|---|---|---|
| DQ1 | DQ1 plus 2 μg/ml PMBN | PMBN only | DQ2 | Cycloserine | |
| E. coli OC2530 (LPS defective) | 8 | 2 | 16 | 8 | 64 |
| E. coli OC2605 | >32 | 4 | 32 | >32 | 16 |
| E. coli OC9040 | >32 | 8 | 64 | >32 | 32 |
| E. coli ATCC 25922 | >32 | 8 | 64 | >32 | 32 |
| E. faecalis ATCC 29212 | >32 | >32 | >64 | 8 | 128 |
| E. faecium OC3312 | >32 | >32 | >64 | 8 | 64 |
| S. aureus ATCC 29213 | >32 | >32 | >64 | 8 | 32 |
| Methicillin-resistant S. aureus OC3726 | >32 | >32 | >64 | 8 | 32 |
| Methicillin-resistant S. aureus OC2878 | >32 | >32 | >64 | 8 | 64 |
| S. aureus OC4172 | >32 | >32 | >64 | 8 | 32 |