FIG. 1.

Study design. Overall, 13 strains simultaneously showed resistance to OFX and injectable agents and were therefore XDR. Among the strains OFX resistant at the baseline, one also showed resistance to AMK and CM, whereas 12 strains which developed OFX resistance during therapy showed resistance to the injectable agents as well. Only one strain from the same patient was included and was either the baseline isolate or the first isolate found to be resistant at follow-up. R, resistance; *, the isolates obtained during therapy were from both amplification (infection with the same strain) and reinfection cases.