TABLE 3.
Effect of lipid II synthesis inhibitors on depolarization of S. aureus by telavancin
| Antibiotica | % Depolarizationb
|
|
|---|---|---|
| Telavancin | Nisin | |
| None | 100 | 100 |
| Fosfomycin | 29 ± 6 | 26 ± 4 |
| d-Cycloserine | 38 ± 8 | 36 ± 1 |
| Bacitracin | 27 ± 4 | 2 ± 1 |
a
S. aureus cells were pretreated for 10 min prior to the addition of telavancin or nisin.
b
Depolarization was calculated relative to that for the control sample without pretreatment. Values represent the means ± standard deviations from at least two independent experiments.