TABLE 5.
MIC ranges, MIC50s, and MIC90s for anaerobic bacteria
| Species (no. of isolates tested) | Antimicrobial agent | MIC (μg/ml)
|
||
|---|---|---|---|---|
| Range | MIC50 | MIC90 | ||
| Bacteroides fragilis (10) | TR-700 | 2-4 | 4 | 4 |
| Linezolid | 4 | 4 | 4 | |
| Metronidazole | 0.12->32 | 0.12 | 1 | |
| Imipenem | 0.12-1 | 0.12 | 0.5 | |
| Bacteroides vulgatus (10) | TR-700 | 1-8 | 2 | 4 |
| Linezolid | 2-4 | 2 | 4 | |
| Metronidazole | 0.12-0.5 | 0.25 | 0.25 | |
| Imipenem | 0.25-0.5 | 0.25 | 0.5 | |
| Bacteroides thetaiotaomicron (10) | TR-700 | 2-4 | 2 | 2 |
| Linezolid | 4-8 | 4 | 8 | |
| Metronidazole | 0.5->32 | 1 | 1 | |
| Imipenem | 0.12-4 | 0.5 | 1 | |
| Bacteroides ovatus (10) | TR-700 | 0.06-8 | 2 | 8 |
| Linezolid | 0.5-8 | 8 | 8 | |
| Metronidazole | 0.5->32 | 1 | 1 | |
| Imipenem | 0.06-0.5 | 0.25 | 0.5 | |
| Clostridium perfringens (10) | TR-700 | 0.25-2 | 0.5 | 2 |
| Linezolid | 2-0 | 2 | 4 | |
| Metronidazole | 1->32 | 1 | >32 | |
| Imipenem | 0.06-1 | 0.12 | 0.5 | |
| Peptostreptococcus anaerobius (10) | TR-700 | 0.12-0.5 | 0.25 | 0.5 |
| Linezolid | 0.5-8 | 1 | 2 | |
| Metronidazole | ≤0.06-1 | 0.5 | 1 | |
| Imipenem | ≤0.03-1 | 0.06 | 1 | |
| Peptostreptococcus micros (10) | TR-700 | 0.12-1 | 0.25 | 0.5 |
| Linezolid | 0.5-2 | 1 | 2 | |
| Metronidazole | ≤0.06->32 | ≤0.06 | >32 | |
| Imipenem | ≤0.03-0.06 | ≤0.03 | ≤0.03 | |
| Porphyromonas asaccharolytica (10) | TR-700 | 0.25-0.5 | 0.25 | 0.5 |
| Linezolid | 0.5-2 | 1 | 2 | |
| Metronidazole | 0.5-2 | 1 | 1 | |
| Imipenem | ≤0.03-0.06 | <0.03 | 0.06 | |
| Prevotella spp. (20) | TR-700 | ≤0.06-16 | 1 | 4 |
| Linezolid | 0.25-16 | 2 | 4 | |
| Metronidazole | ≤0.06->32 | 0.5 | >32 | |
| Imipenem | ≤0.03-16 | ≤0.06 | 1 | |