FIG. 3.

Neutrophils and complement components limit Hib colonization. The density of Hib PC⁺ at 3 days p.i. in the nasal lavage fluid of BALB/c mice treated with rat IgG (control), RB6-85C (i.p. antibody treatment to deplete neutrophil-like cells), CVF (i.p. CVF pretreatment to deplete complement), or RB6-85C and CVF. The log CFU/ml of Hib in the lavage fluid is indicated for each mouse, and horizontal bars denote mean values. The dashed line indicates the limit of detection. Statistical differences were determined using the Mann-Whitney test (*, P < 0.05; **, P < 0.01).