TABLE 5.

Number of transcripts upregulated in joint tissues of ISCL and C3H or B6 parental mice at 1 week following infection^a

Mouse strain	Arthritis phenotypeb	No. of transcripts upregulated in both ISCL mice and:
		C3H mice (characterized by severe arthritis phenotype)	B6 mice (characterized by mild arthritis phenotype)
C3.B6-Bbaa2-Bbaa3	Intermediate	114	6
C3.B6-Bbaa4	Intermediate	208	8
B6.C3-Bbaa2-Bbaa3	Intermediate	25	5
B6.C3-Bbaa4	Intermediate	33	6

^aThe number of transcripts upregulated >2-fold at 1 week postinfection, relative to transcripts in samples from uninfected controls, was determined for each ISCL and for wild-type C3H and B6 mice. The transcripts upregulated by infection in each ISCL were then compared with those induced in either C3H or B6 mice, and the number upregulated in both groups in each comparison is indicated. Numbers were determined using a single probe set for each gene or expressed sequence tag with NetAfx intersection analysis.

^bPhenotype relative to those of wild-type C3H and B6 mice.