FIG. 3.

Real-time PCR analysis of dosT and dosS mutant strains during aerobic growth and day 6 of the anaerobic dormancy model. dosT mutant strain levels remain relatively constant during anaerobiosis with or without the presence of DosR, and dosS mutant strain levels serve as a control for DosR regulon induction. Transcript levels are normalized to those of Rv0239. Standard deviation is indicated. White bars represent the transcript level of dosT and black bars represent the level of dosS in the noted strains. No significant difference in the dosT copy number exists between H37Rv aerobic growth and anaerobic dormancy at day 6 or ΔdosR mutant strain aerobic growth and anaerobic dormancy at day 6.