FIG. 3.
Structure of the DegP hexamer in the closed conformation. Surface representations are shown as viewed along the threefold axis (A) and from the side (B). The color and label schemes are identical to those in Fig. 2. In this conformation, the PDZ domains from each monomer within a trimer (labeled in black) interact with the PDZ domains of the monomers in the opposite trimer (labeled in blue), closing the side entrances to the inner chamber. The surface representations on the right each show one of the monomers as a ribbon docked into the semitransparent volume. These images were prepared from PDB file 1KY9 by using the EMAN (25) and Chimera (28) programs as described in the legend to Fig. 2. Prot, protease domain.