TABLE 2.
Gene conversion is biased toward gain of markers in all the HJ migration mutants
| Strain (relevant genotype) | No. of gene conversion tracts with:
|
P valuea | |
|---|---|---|---|
| Gain of markers | Loss of markers | ||
| CFNX55 (wild type) | 85 | 25 | 9 × 10−9 |
| CFNX728 (ruvB::loxPSp) | 28 | 9 | 0.0015 |
| CFNX729 (recG::loxPSp) | 43 | 4 | 1 × 10−8 |
| CFNX730 (radA::loxPSp) | 36 | 9 | 5 × 10−5 |
| CFNX732 (ruvB::loxP recG::loxPSp) | 29 | 11 | 0.0035 |
| CFNX733 (ruvB::loxP radA::loxP) | 29 | 15 | 0.025 |
| CFNX734 (recG::loxP radA::loxPSp) | 40 | 8 | 3 × 10−6 |
a
Probability that the observed distribution agrees with the null expectation (gene conversion toward gain of markers being equal to gene conversion toward loss of markers), evaluated by a nonparametrical binomial test. All P values are significant at the 5% level.