TABLE 2.

Summary of the main characteristics identified in the genetic modules in the three different groups of temperate bacteriophages

Phage group	Cluster members	Lysogeny module		Replication module		No. of genes for packaging module	Morphology module		Lysis module
		No. of genes	Integrase	No. of genes	Peculiarity(ies)a		No. of genes	Peculiarity(ies)b	No. of genes	Peculiarity(ies)
1	φSpn_OXC/φSpn_3	12	Int1	16	cg1	4	15	Sfi21-like genus; pblB-like	4	Holin 1, holin 2
	φSpn_11	8	Int1	22	cg1, cg2	5	14	Sfi11-like genus; pblAB-like	4	Holin 1, holin 2
	φSpn_14	12	Int1	20	cg1, cg2	3	17	Sfi21-like genus; pblB-like	4	Holin 1, holin 2
2	φSpn_6	7	Int2	27	cg1, cg2; TA system; vapE-like gene	3	21	Sfi11-like genus; pblB-like	4	Holin 1-holin 2
	φSpn_9	8	Int2	25	cg1, cg2; vapE-like gene	3	20	Sfi11-like genus; pblB-like	4	Holin 1
	φSpn_19	7	Int2	25	cg1, cg2; vapE-like gene	3	19	Sfi11-like genus; pblB-like	4	Holin 1
	φSpn_23	8	Int2	30	cg2; vapE-like gene	3	21	Sfi11-like genus; pblB-like	4	Holin 1, holin 2
3	MM1-2008	5	Int2	24	cg1, cg2; C5-MTase (α and β subunits)	3	17	Sfi11-like genus	4	Holin 1, holin 2
	φSpn_18	7	Int3	22	cg1, cg2; C5-MTase	3	17	Sfi11-like genus	4	Holin 1, holin 2

^acg, conserved genes identified in the replication module. TA system, toxin/antitoxin system (MazEF-like).

^bSfi21/Sfi11-like genus indicate the genus of Siphoviridae phages as previously proposed (10).