Influenza A virus establishes infection and replicates in WT, Bax KO, Bak KO, and Bax/Bak DKO cells. Actin was stained by phalloidin-TRITC (A, D, G, and J). Immunocytochemical staining of influenza A virus-infected cells at 24 hpi with anti-WSN whole-virus primary antibody, followed by Alexa Fluor 488 staining (B, E, H, and K). Reveals cytoplasmic influenza A virus-induced vesicles containing mature virions in all infected cells regardless of Bax and/or Bak activity. (C, F, I, and L) Merge. Bars, 10 μm.