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Phenotypic summary of segment 2 mutants
| Virus | Predicted structure of ORFs
|
Major phenotype(s) | Replication kinetics | ||
|---|---|---|---|---|---|
| PB1 | PB1-F2 | N40 | |||
| F2-8 | M40I | Δ8 | Null | WT | |
| F2-57 | WT | Δ57 | WT | WT | |
| ΔAUG | WT | Null | WT | Overexpresses N40; delayed PB1 expression; increased cytoplasmic PB1 | WT |
| M40L | M40L | WT | Null | Early increase in PB1 | Delayed |
| M40I | M40I | W9L | Null | Early increase in PB1 | Delayed |
