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. 2009 Jun 10;83(16):8032–8040. doi: 10.1128/JVI.00332-09

FIG. 9.

FIG. 9.

The four conserved cysteine residues in WHV Pol are also critical for encapsidation. The four alanine substitution mutants of WHV Pol (C162A, C173A, C177A, and C06A) were made in parallel, and the positions of the four conserved cysteine residues are indicated by asterisks in Fig. 3A. The four WHV Pol mutants were tested for their ability to support the encapsidation of HBV pgRNA by complementing the HBV Pol-null construct. RPA and Western blot (WB) analysis were performed as described in the legend to Fig. 2.