Skip to main content
. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Ann N Y Acad Sci. 2008 Dec;1148:223–231. doi: 10.1196/annals.1410.061

Figure 2.

Figure 2

A physiological homeostatic system. As the level of the monitored variable changes, afferent information is compared with a set point or other algorithm for responding, and the sensed discrepancy leads to altered activities of effectors. Note the odd number of (-) signs, indicating a negative feedback loop. In response to a continuous perturbation, the level of the monitored variable reaches an apparent steady state.