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. Author manuscript; available in PMC: 2009 Jul 26.
Published in final edited form as: Biochem Soc Trans. 2008 Oct;36(Pt 5):1037–1044. doi: 10.1042/BST0361037

Table 3.

Summary of 4HNE modifications* of hBAT identified at varying 4HNE concentrations

4HNE concentration (µM)
Modified peptide sequence 8 16 32 64 128


1MIQLTATPVSALVDEPVHIR20 H18 H18
51RANEFGEVDLNHASSLGGDMYMGVHPMGLFWSLKPEK86 H62 H62, H74 H62, H74 H62, H74 H62, H74
271HGQIHQPLPHSAQL284 H271, H280 H271, H280 H271, H275 H271, H275 H271, H275
H280 H280 H280
316AQGQFLFIVGEGDKTINSK334 K329, K334 K329, K334 K329, K334 K329, K334 K329, K334
335AHAEQAIGQLKR346 H336 H336 H336 H336 H336
350NNWTLLSYPGAGHLIEPPYSPLCCASTTHDLR381 H362 H362 H362 H362 H362, C372
C373, H378
381RLHWGGEVIPHAAAQEHAWK400 H397 H397 H397 H397
*

all these modifications were Michael adducts