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. 2009 Aug 5;4(8):e6507. doi: 10.1371/journal.pone.0006507

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Kroener et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) Representative traces illustrating the effects of 5 µM cocaine on cortical Up-states evoked by VTA-stimulation. B) Altering DA transmission with cocaine (5 or 10 µM, N = 10) resulted in transient reductions in Up-state duration and spike number during the Up-state (Level of significance * P<0.05, and ** P<0.01, compared to baseline, paired Student's t-tests).