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. Author manuscript; available in PMC: 2009 Jul 27.
Published in final edited form as: Int J Cancer. 2009 Apr 15;124(8):1980–1989. doi: 10.1002/ijc.24139

Figure 4.

Figure 4

Inhibition of NF-κB activity by IκBα-M sensitizes prostate cancer cells to TRAIL- and TNFα-induced apoptosis. (A) NF-κB luciferase activity (top panel), cell viability (middle panel) of PC3 cells with ectopic expression of IκBα-M or control vector (Western blot -- bottom panel) with or without TNFα treatment for 24 hours. (B) NF-κB luciferase activity (top panel), cell viability (middle panel) of PC3-TR cells with ectopic expression of IκBα-M or control vector (Western blot -- bottom panel) with or without TRAIL or TNFα treatment for 24 hours. Transfection of empty vector was used as control (−). Cell viability was measured by MTT assay. Error bars (SD) are results of at least three independent experiments. “*” Refers to statistically significant differences between indicated groups.