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. Author manuscript; available in PMC: 2009 Jul 27.
Published in final edited form as: Int J Cancer. 2009 Apr 15;124(8):1980–1989. doi: 10.1002/ijc.24139

Figure 6.

Figure 6

Concomitant inhibition of NF-κB and potentiation of AP-1 activities markedly changes TRAIL- or TNFα-resistance in prostate cancer cells. (A) Simultaneous ectopic expression of c-Fos and IκBα-M in prostate cancer PC3, PC3-TR and LNCaP cells. (B) TRAIL-induced cell death in PC3-TR and LNCaP cells before and after co-transfection of c-Fos and IκBα-M. (C) TNFα-induced cell death in PC3 and PC3-TR cells before and after co-transfection of c-Fos and IκBα-M. Error bars (SD) are results of at least three independent experiments. “*” Refers to statistically significant differences between indicated groups.