Table 6.

Results of regression analysis of gene groups [‘pathway’ components] in NYHP European Americans

Gene group	Genes in the group	BMI
		raw p value	R2	adjusted R2
1	LEP, LEPR, SOCS3, JAK2, STAT3	0.22	0.099	0.009
2	AGRP, CPE, MC4R, POMC	0.64	0.040	−0.002
3	GHRL, GHSR	0.03	0.027	0.010
4	GCG, GLP1R	0.01	0.033	0.011
5	NPY1R, NPY5R	0.12	0.012	0.002
6	HTR2A, HTR2C	0.16	0.056	0.007
7	BBS1, BBS2, BBS3, BBS4, BBS5, BBS6, BBS7, BBS8	0.40	0.036	0.002

For none of the genes were the FDR values less than 0.05.