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. Author manuscript; available in PMC: 2009 Jul 27.
Published in final edited form as: Clin Cancer Res. 2007 Apr 1;13(7):2261–2270. doi: 10.1158/1078-0432.CCR-06-2468

Table 3.

Parameter estimates for single and combined drug effects of ATO and 17-DMAG on cell-survival.

Parameter Parameter Description Estimate CV%
Smax,ATO Cell-Killing Rate Constant For ATO 0.845 7.8
Smax,17-DMAG Cell-Killing Rate Constant For 17-DMAG 0.118 15
ksyn Natural Cell Synthesis Rate Constant 0.0671 N/A
Xmax Maximal Number of Cells 1530 N/A
knat Rate of Natural Cell-Death 0.00202 N/A
γ Interaction Parameter 0.0443 18.3