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Vinylation of aryl iodides using polyvinylsiloxane 19
 | |||||
|---|---|---|---|---|---|
| Entry | R | 19 (equiv.) | TBAF (equiv.) | t/min | Yield (%) |
| 1 | 4-C(O)Me | 0.3 | 2.0 | 10 | 88 |
| 2 | 4-COOEt | 0.3 | 2.0 | 10 | 85 |
| 3a | 4-COOEt | 0.3 | 2.0 | 60 | 83 |
| 4b | 4-OMe | 0.375 | 3.0 | 360 | 63 |
| 5 | 3-NO2 | 0.3 | 2.0 | 10 | 87 |
| 6 | 3-CH2OH | 0.3 | 2.0 | 480 | 59 |
| 7b | 2-OMe | 0.375 | 3.0 | c | 72 |
| 8 | 2-COOMe | 0.3 | 2.0 | 480 | 83 |
| 9 | d | 0.3 | 2.0 | 180 | 64 |
Pd(dba)2 (1 mol%) used.
Ph3As (10 mol%) added to the reaction.
24 h.
1-Iodonaphthalene.
