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. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Clin Cancer Res. 2008 Nov 1;14(21):6839–6846. doi: 10.1158/1078-0432.CCR-08-0230

(A) MMP-9 production by monocyte-derived macrophages incubated with 0 and 0.1 μM hydrocortisone and 1 μM norepinephrine with supernatants harvested at 2 and at 6 hours. MMP-9 levels (pg/mL) were analyzed by ELISA. (B) MMP-9 production by monocyte-derived macrophages incubated with 0 and 1 μM norepinephrine with supernatants harvested at 2, 4, 6, 12 and 24 hours. MMP-9 levels (pg/mL) were analyzed by ELISA. Repeated measures ANOVA indicated a significant effect for condition over time (p=0.001). All data points represent the mean of 2 experiments. Significant differences as compared to the control wells (with media alone added to the cells) are indicated. Error bars represent standard error of the mean.

(A) MMP-9 production by monocyte-derived macrophages incubated with 0 and 0.1 μM hydrocortisone and 1 μM norepinephrine with supernatants harvested at 2 and at 6 hours. MMP-9 levels (pg/mL) were analyzed by ELISA. (B) MMP-9 production by monocyte-derived macrophages incubated with 0 and 1 μM norepinephrine with supernatants harvested at 2, 4, 6, 12 and 24 hours. MMP-9 levels (pg/mL) were analyzed by ELISA. Repeated measures ANOVA indicated a significant effect for condition over time (p=0.001). All data points represent the mean of 2 experiments. Significant differences as compared to the control wells (with media alone added to the cells) are indicated. Error bars represent standard error of the mean.