Figure 1.

Small molecules alter development of the central nervous system. (A) Untreated zebrafish embryo. (B) Embryo treated with the small molecule 32N8 at a concentration of 2 μg/ml. The enlarged hindbrain ventricle is indicated by an arrowhead. (C) Embryo treated with the small molecule 33M20 (2 μg/ml). The folds in the notochord are indicated by arrowheads. (D) Embryo treated with the small molecule 32N5 (2 μg/ml). Hindbrain projections are indicated by arrowheads. All embryos were photographed 25 hpf.