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Increased circulating and myocardial trophic factors. A: circulating (plasma) levels of hepatocyte growth factor (HGF), leukemia inhibitory factor (LIF), and granulocyte/macrophage colony-stimulating factor (G/M-CSF) 1 mo after MSC administration (n = 3 animals/group). B: heart tissues were collected 1 mo after MSC administration and homogenized. Clarified lysates were assayed by HGF, IGF-II, and VEGF ELISA kits (n = 4 animals/group). *P < 0.05 vs. the HBSS control.
