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Relationship of expression of ecSOD (mRNA) to maximal relaxation of aorta to acetylcholine in adult and old wild-type and ecSOD−/− mice. In adult mice, there was a significant correlation between expression of ecSOD (SOD3) and relaxation to acetylcholine (P < 0.05, slope = 15.2). In old mice, there also was a significant correlation (P < 0.05, slope = 43.9), which was significantly different from the slope in adult mice (P < 0.05).
