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. Author manuscript; available in PMC: 2009 Jul 27.
Published in final edited form as: Angiogenesis. 2009 Feb 14;12(2):165–175. doi: 10.1007/s10456-009-9136-6

Figure 1. Schematic structure of FN.

Figure 1

FN is composed of structural repeats of three types. Type I repeats are designated in pink, type II repeats are in orange and type III repeats are in cyan (the 9th and 10th repeats are marked). Alternatively spliced EIIIA, EIIIB and V regions are marked. The stippled part of the V region can be included (V120 isoform) or excluded (V95 isoform) in the mouse. Red dots indicate integrin-binding sites in the 10th type III repeat and in the V region. Integrins known to bind these sites and EIIIA are listed.