Figure 3).

Intracellular Ca²⁺ concentration ([Ca²⁺]_i) at baseline, 5 min reperfusion and end reperfusion. Rat hearts were subjected to A) control perfusion and ischemic preconditioning (IPC) ± N-2-mercaptopropionyl glycine (2-MPG) (400 μM); and B) control perfusion and pharmacological preconditioning with diazoxide (DZ) (100 μM) ± 2-MPG (400 μM). All values are expressed as mean ± SEM (n=5). Statistical significance was determined using one-way ANOVA with Bonferroni’s post-test. ^#IPC, 2-MPG and IPC plus 2-MPG were significantly different versus the control (P<0.01). *DZ, 2-MPG and 2-MPG plus DZ were significantly different versus the control (P<0.01)