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Early and delayed effects of 7-oxo-prostacyclin (7-oxo-PGI2) on ischemia and reperfusion-induced ventricular arrhythmias in anesthetized dogs. The number of extrasystoles (ES/min) during phase I (0 min to 10 min) and phase II (10 min to 25 min) of occlusion of the left anterior descending coronary artery and following reperfusion is shown in control (C) dogs and in dogs treated with 7-oxo-PGI2 2 h, 6 h, 24 h, 48 h and 72 h before the ischemia-reperfusion insult
