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Effect of poly(ADP-ribose) polymerase (PARP) inhibitors on Akt phosphorylation. Ischemia-reperfusion (IR) without any treatment triggered moderate phosphorylation of Akt (p-Akt). Both PARP inhibitors could further enhance the phosphorylation. *P<0.05. IR+4OHQ IR in the presence of 100 μM 4-hydroxyquinazoline; IR+HO3089 IR in the presence of 25 μM HO-3089; N Normoxia
